Serological Relationships of Type-specific and Degraded Pneumococci

Serological survey of sheep in Iran for Type specific Antibody to Bluetongue virus

Antibody Formation in Volunteers following Injection of Pneumococci or Their Type-specific Polysaccharides

1. A modification of the microanalytical quantitative precipitin method, five to ten times as sensitive as the older procedure, has been used to measure the type-specific antibody response in human beings. Injections of type-specific pneumococci or equivalent amounts of their type-specific polysaccharides led to comparable antibody production. In general, the few hundredths of a milligram of po...

Immunological Properties of a Typical (s-producing) and a Degraded (non-s-producing) Strain of Type Ii Pneumococcus with Special Reference to Protective Antibodies

The loss of the specialized function of S production by Type II pneumococcus was accompanied by a loss of the antigenic properties involved in both active and passive protection of mice. Absorption of Type II serum with S-producing pneumococci removed all the protective antibodies, as well as the type-specific agglutinins and S precipitins. The same absorption treatment of the serum by non-S-pr...

Serological Studies on Sugar

Solutions of all of the C. P. sucrose reagents of American manufacture that were tested gave reactions with Type II antipneumococcus serum. The capacity of that antiserum to react with sucrose solutions was removed by absorption with the homologous pneumococci or with Leuconostoc mesenteroides. The serological reactivity was due not to sucrose itself but to accompanying substances that could be...

Studies on Immunological Relationships among the Pneumococci

Mice vaccinated with yeast were protected against subsequent infection with Type II pneumococci, but not against Types I or III. While the protection was not universal, as high a percentage of mice acquired active anti-Type II immunity, as was obtained by vaccination of another group of mice with Type II pneumococci themselves. This specific protection of mice by active immunization with the ye...